Format

Send to

Choose Destination
Kidney Int. 2010 Mar;77(6):487-9. doi: 10.1038/ki.2009.544.

Better nephrology for mice--and man.

Author information

1
Biotechnology Discovery Research, Lilly Research Laboratories, Indianapolis, Indiana 46285, USA. breyer_matthew@lilly.com

Abstract

The use of creatinine to estimate glomerular filtration rate in patients is prone to well-described artifacts that impact its interpretation. Eisner et al. now show that the impact of creatinine secretion on creatinine clearance is even larger in mice than in humans, raising questions regarding the utility of creatinine for measuring glomerular filtration rate in mice.

PMID:
20186162
DOI:
10.1038/ki.2009.544
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center