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Behav Med. 2010 Jan-Mar;36(1):32-6. doi: 10.1080/08964280903521339.

Progressive increase of anxiety and depression in patients waiting for a kidney transplantation.

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INSERMU 669, Department of Psychiatry, Bicêtre University Hospital, Paris XI University, Assistance Publique-Hôpitaux de Paris, 78 Rue du Général Leclerc, 94230 Le Kremlin Bicêtre, France.


Because of the increasing duration of the waiting-list period for kidney transplantation, we hypothesized that this period was associated with a progressive increase in depressive and anxious symptoms in patients waitlisted for a kidney transplantation. In a prospective naturalistic follow-up cohort study, 390 patients on a waiting list for kidney transplant were assessed for anxiety and depression at the time of inclusion on the waiting list, 12 months later, 24 months later, and 3 months after transplantation. The Beck Depression Inventory-Short Version (Short-BDI) and the State and Trait Anxiety Inventory (STAI) were used for this assessment. We found that in this sample, anxious and depressive symptoms progressively increased before transplantation and showed a marked decrease after transplantation. We conclude that to limit anxious and depressive symptoms in patients waiting for a kidney transplantation, the duration of the waiting list period should be reduced as far as possible.

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