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Cases J. 2009 Apr 3;2:6637. doi: 10.1186/1757-1626-0002-0000006637.

Pyrogen reaction and conversion of sustained ventricular tachycardia to sinus rhythm: two case reports.

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Institute of Geriatric Cardiology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China and Department of Internal Medicine, People's Hospital of Wuzhi County, Xinghua Road 120, Wuzhi County, 454950, Henan Province, China.



Pyrogen reaction is a side effect of intravenous infusion of solution on body; sustained ventricular tachycardia is a serious arrhythmia, no relationship between them has been reported before.


Two patients with sustained ventricular tachycardia refractory to lidocaine happened to have pyrogen reaction. The sustained ventricular tachycardia was converted to sinus rhythm after the pyrogen reaction.


The conversion of sustained ventricular tachycardia might be related to pyrogen reaction. The effects of pyrogen reaction on sustained ventricular tachycardia need further research.

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