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Neurosurgery. 2010 Mar;66(3 Suppl Operative):E121-3; discussion E123. doi: 10.1227/01.NEU.0000348560.85056.63.

Delineation of the nucleus centre median by proton density weighted magnetic resonance imaging at 3 T.

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1
Department of Neurology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany. martin.kanowski@medizin.uni-magdeburg.de

Abstract

OBJECTIVE:

To demonstrate that proton density weighted magnetic resonance imaging (MRI) at 3 T accomplishes delineation of the centre median (CM) complex from surrounding thalamic tissue and may improve targeting accuracy in stereotactic neurosurgery.

METHODS:

Five healthy subjects (1 man, 4 women; age range 22-35 years) underwent high-resolution MRI at 3 T with different imaging parameters in order to optimize the direct visualization of the CM.

RESULTS:

In healthy subjects, the CM complex of the thalamus can be reliably contrasted on axially oriented slices by means of proton density weighted turbo-spin-echo MRI. An in-plane resolution of at least 0.6 x 0.6 mm2 is crucial at a slice thickness between 2 and 3 mm. Effective suppression of head motion is essential.

CONCLUSION:

MRI-based delineation of the CM could have therapeutic potential to facilitate target determination for neuromodulation in stereotactic neurosurgery.

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