Format

Send to

Choose Destination
See comment in PubMed Commons below
Vet Pathol. 2010 Mar;47(2):334-8. doi: 10.1177/0300985809359054. Epub 2009 Dec 31.

Brachyspira murdochii colitis in pigs.

Author information

1
National Veterinary Institute, Technical University of Denmark, Copenhagen, Denmark. tije@vet.dtu.dk

Abstract

The weakly beta-hemolytic porcine spirochete Brachyspira murdochii is considered a normal intestinal commensal. In the present study, however, a field case of B murdochii-associated catarrhal colitis was identified in a pig, as characterized by extensive spirochetal colonization of the surface epithelium. Experimentally, 8 weaned pigs were challenged with the B murdochii isolate, reproducing catarrhal colitis in 2 animals. By applying fluorescent in situ hybridization using a species-specific oligonucleotide probe targeting 23S rRNA, B murdochii organisms were found in high numbers and were closely associated with the surface epithelium in the pigs with catarrhal colitis. The results indicate that, when present in high numbers, B murdochii is low pathogenic for pigs.

PMID:
20173181
DOI:
10.1177/0300985809359054
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Support Center