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Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S94-100. doi: 10.1016/j.ijrobp.2009.06.092.

Radiation-associated liver injury.

Author information

1
Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI 48109-5010, USA. cpan@umich.edu

Abstract

The liver is a critically important organ that has numerous functions including the production of bile, metabolism of ingested nutrients, elimination of many waste products, glycogen storage, and plasma protein synthesis. The liver is often incidentally irradiated during radiation therapy (RT) for tumors in the upper- abdomen, right lower lung, distal esophagus, or during whole abdomen or whole body RT. This article describes the endpoints, time-course, and dose-volume effect of radiation on the liver.

PMID:
20171524
PMCID:
PMC4388033
DOI:
10.1016/j.ijrobp.2009.06.092
[Indexed for MEDLINE]
Free PMC Article

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