Send to

Choose Destination
See comment in PubMed Commons below
Curr Pharm Biotechnol. 2010 Feb;11(2):167-74.

Cell-penetrating peptide technology to deliver chaperones and associated factors in diseases and basic research.

Author information

Dep. 828, Molecular Neurobiology, Ottiliavej 9, DK-2500 Valby, Denmark.


Cell-penetrating peptides (CPP), also called protein transduction domains (PTD), membrane-permeable peptides (MPP), or Trojan horse peptides, have been used in many different research areas. The delivery of heat shock proteins (Hsp) using CPP has been applied in models for apoptosis, necrosis, oxidative stress, neurodegenerative diseases, stroke, cystic fibrosis, smooth muscle relaxation, myocardial injury, scar formation, and others. This review summarizes the accomplishments of the field over the last years and discusses why Hsp are particularly suitable for CPP-mediated delivery.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Bentham Science Publishers Ltd.
    Loading ...
    Support Center