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Dev Cell. 2010 Feb 16;18(2):175-89. doi: 10.1016/j.devcel.2010.01.011.

Organogenesis and development of the liver.

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  • 1Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.

Abstract

Embryonic development of the liver has been studied intensely, yielding insights that impact diverse areas of developmental and cell biology. Understanding the fundamental mechanisms that control hepatogenesis has also laid the basis for the rational differentiation of stem cells into cells that display many hepatic functions. Here, we review the basic molecular mechanisms that control the formation of the liver as an organ.

PMID:
20159590
DOI:
10.1016/j.devcel.2010.01.011
[PubMed - indexed for MEDLINE]
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