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Neuron. 2010 Feb 11;65(3):298-308. doi: 10.1016/j.neuron.2009.12.022.

Imaging the human medial temporal lobe with high-resolution fMRI.

Author information

1
Department of Psychology, Stanford University, Stanford, CA 94305, USA. valerie.carr@stanford.edu

Abstract

High-resolution functional MRI (hr-fMRI) affords unique leverage on the functional properties of human medial temporal lobe (MTL) substructures. We review initial hr-fMRI efforts to delineate (1) encoding and retrieval processes within the hippocampal circuit, (2) hippocampal subfield contributions to pattern separation and pattern completion, and (3) the representational capabilities of distinct MTL subregions. Extant data reveal functional heterogeneity within human MTL and highlight the promise of hr-fMRI for bridging human, animal, and computational approaches to understanding MTL function.

PMID:
20159444
PMCID:
PMC2844113
DOI:
10.1016/j.neuron.2009.12.022
[Indexed for MEDLINE]
Free PMC Article
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