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Database (Oxford). 2009;2009:bap008. Epub 2009 Aug 4.

miRò: a miRNA knowledge base.

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1
Department of Biomedical Sciences, University of Catania, Italy, 95124, Department of Mathematics and Computer Sciences, University of Catania, Catania, Italy, 95125 and Courant Institute of Mathematical Sciences, New York University, New York, USA, 10012-1185.

Abstract

miRò is a web-based knowledge base that provides users with miRNA-phenotype associations in humans. It integrates data from various online sources, such as databases of miRNAs, ontologies, diseases and targets, into a unified database equipped with an intuitive and flexible query interface and data mining facilities. The main goal of miRò is the establishment of a knowledge base which allows non-trivial analysis through sophisticated mining techniques and the introduction of a new layer of associations between genes and phenotypes inferred based on miRNAs annotations. Furthermore, a specificity function applied to validated data highlights the most significant associations. The miRò web site is available at: http://ferrolab.dmi.unict.it/miro.Database URL:http://ferrolab.dmi.unict.it/miro.

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