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Nutr Cancer. 2009;61(6):836-41. doi: 10.1080/01635580903285056.

Review: green tea polyphenols in chemoprevention of prostate cancer: preclinical and clinical studies.

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1
Department of Dermatology, University of Wisconsin, Madison, Wisconsin 53706, USA.

Abstract

The prevention of prostate cancer (PCa) is a crucial medical challenge in developed countries. PCa remains surrounded by puzzles in spite of the considerable progress in research, diagnosis, and treatment. It is an ideal target for chemoprevention, as clinically significant PCa usually requires more than two decades for development. Green tea and its major constituent epigallocatechin gallate (EGCG) have been extensively studied as a potential treatment for a variety of diseases including cancer. In this review, we highlight the evidences of green tea polyphenols from preclinical and clinical studies in the chemoprevention/chemotherapy of PCa.

PMID:
20155624
PMCID:
PMC2991093
DOI:
10.1080/01635580903285056
[Indexed for MEDLINE]
Free PMC Article

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