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Adv Drug Deliv Rev. 2010 Jun 15;62(7-8):753-64. doi: 10.1016/j.addr.2010.02.003. Epub 2010 Feb 11.

Scaffold-free cell delivery for use in regenerative medicine.

Author information

1
Competence Center for Applied Biotechnology and Molecular Medicine, University of Zurich, Switzerland.

Abstract

The development of cell-based therapies for diseased tissues is one of the most promising research directions in regenerative medicine. Cell-delivery methods are an essential part of cell therapy concepts. Therapies with the potential to become clinical routine will only be possible if these methods ensure efficient engraftment and therapeutically-relevant number of cells survive. Here we provide an overview of three different scaffold-free cell-delivery concepts: (i) single cell delivery, (ii) cell sheet engineering and (iii) microtissue technology.

PMID:
20153387
DOI:
10.1016/j.addr.2010.02.003
[Indexed for MEDLINE]

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