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Pediatr Radiol. 2010 Aug;40(8):1421-5. doi: 10.1007/s00247-009-1539-4. Epub 2010 Feb 12.

Xanthogranulomatous pyelonephritis: an uncommon pediatric renal mass.

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Department of Radiology, University of Michigan Health System, C. S. Mott Children's Hospital, 1500 E. Medical Center Dr., Ann Arbor, MI 48103, USA.


Xanthogranulomatous pyelonephritis (XGP) is a chronic suppurative infectious process that only rarely affects pediatric patients, and most commonly occurs in the setting of a large obstructing calculus. Histologically, XGP is characterized by the presence of chronic inflammation and lipid-laden macrophages. This case report illustrates the radiological, surgical, and pathologic findings in a young patient who presented to our institution for treatment of this uncommon condition. Although rare, xanthogranulomatous pyelonephritis is a clinically important entity that can affect pediatric patients. This condition should be considered in the differential diagnosis for an atypical-appearing renal mass.

[Indexed for MEDLINE]

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