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Curr Opin Microbiol. 2010 Apr;13(2):184-9. doi: 10.1016/j.mib.2010.01.009. Epub 2010 Feb 10.

Two-component signaling circuit structure and properties.

Author information

1
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA. goulian@sas.upenn.edu

Abstract

Various modeling and experimental studies have analyzed the reactions, interconnections, and motifs in two-component systems, with an eye toward understanding their physiological implications and the differences between alternative designs. Examples where recent progress has been made include aspects of autoregulation, signal integration in branched pathways, cross-talk suppression, and cross-regulation via connector proteins.

PMID:
20149717
PMCID:
PMC2847654
DOI:
10.1016/j.mib.2010.01.009
[Indexed for MEDLINE]
Free PMC Article

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