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J Autism Dev Disord. 2010 Jun;40(6):689-703. doi: 10.1007/s10803-009-0915-0.

Improved diagnostic validity of the ADOS revised algorithms: a replication study in an independent sample.

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1
Karakter Child and Adolescent Psychiatry University Center, Reinier Postlaan 12, 6525 GC Nijmegen, The Netherlands. i.oosterling@karakter.com

Abstract

Recently, Gotham et al. (2007) proposed revised algorithms for the Autism Diagnostic Observation Schedule (ADOS) with improved diagnostic validity. The aim of the current study was to replicate predictive validity, factor structure, and correlations with age and verbal and nonverbal IQ of the ADOS revised algorithms for Modules 1 and 2 in a large independent Dutch sample (N = 532). Results showed that the improvement of diagnostic validity was most apparent for autism, except in very young or low functioning children. Results for other autism spectrum disorders were less consistent. Overall, these findings support the use of the more homogeneous revised algorithms, with the use of similar items across developmental cells making it easier to compare ADOS scores within and between individuals.

PMID:
20148299
PMCID:
PMC2864898
DOI:
10.1007/s10803-009-0915-0
[Indexed for MEDLINE]
Free PMC Article
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