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Ophthalmologica. 2010;224(4):251-7. doi: 10.1159/000284351. Epub 2010 Feb 10.

Screening for diabetic retinopathy: a comparative trial of photography and scanning laser ophthalmoscopy.

Author information

1
Department of Ophthalmology, Ninewells Hospital and Medical School, Dundee, UK.

Abstract

AIMS:

To evaluate the sensitivity and specificity of wide-field scanning laser ophthalmoscopy (WSLO) in the detection of referable diabetic eye disease, and to compare its performance with digital retinal photography.

METHODS:

Patients enrolled into the study underwent non-mydriatic WSLO imaging, then single- and dual-field mydriatic digital retinal photography, and examination with slit lamp biomicroscopy, the reference standard. Grading of retinopathy was performed in a masked fashion.

RESULTS:

A total of 380 patients (759 eyes) were recruited to the study. Technical failure rates for dilated single-field retinal photography, dual-field retinal photography and undilated WSLO were 6.3, 5.8 and 10.8%, respectively (0.005 < p < 0.02 for photography vs. WSLO). The respective indices for screening sensitivity were 82.9, 82.9 and 83.6% (p > 0.2). Specificity was 92.1, 91.1 and 89.5%, respectively (p > 0.2).

CONCLUSIONS:

Sensitivity and specificity for WSLO were similar to retinal photography. The technical failure rate was greater for the WSLO used in this study.

PMID:
20145421
DOI:
10.1159/000284351
[Indexed for MEDLINE]
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