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J Virol Methods. 2010 Jul;167(1):100-2. doi: 10.1016/j.jviromet.2010.02.001. Epub 2010 Feb 6.

A rapid test for the detection of influenza A virus including pandemic influenza A/H1N1 2009.

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1
National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science, Xiamen University, 422 South Siming Rd., Xiamen, China.

Abstract

A new rapid diagnostic test for detection of influenza A virus was evaluated with four sets of experiments: first, a comparison with a commercial diagnostic kit against a panel of virus strains was conducted; second, the kit was tested against a collection of 40 strains of influenza A virus isolated from five different host species and 26 strains of other respiratory viruses used as controls; third, the kit was tested against specimens collected in the field obtained from human and chicken; and fourth, the kit was tested against the novel pandemic influenza A/H1N1 2009 clinical specimens obtained from admitted to hospital patients. The test kit displayed a sensitivity of 88% for both human specimens and avian specimens. The corresponding specificity was 99.3% for human specimens and 96.5% for avian specimens. This test kit may be useful for rapid diagnosis of influenza A virus.

PMID:
20144656
DOI:
10.1016/j.jviromet.2010.02.001
[Indexed for MEDLINE]
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