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J Indian Soc Periodontol. 2008 Jan;12(1):26-7. doi: 10.4103/0972-124X.44095.

Periodontal considerations for Glanzmann's thrombasthenic patient.

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Ex-Postgraduate Student, Department of Periodontics, M.S. Ramaiah Dental College and Hospital, MSRIT Post, Bangalore - 560 054, India.


Glanzmann's thrombasthenia (GT) was reported and described as a bleeding diathesis seen in children and characterized by diminished clot retraction. The disorder is caused by a deficiency in the platelet membrane glycoprotein IIb-IIIa complex, with bleeding due to defective platelet hemostatic plug formation. The recurrent features of GT include purpura, epistaxis, gingival hemorrhage, and menorrhagia. GT being an autosomal recessive trait is reported to be especially prevalent in populations where intermarriage is common. Typically, the patients are diagnosed in infancy within the age of five. Though no differences appear to occur based on sex men more frequently present with gingival bleeding. We report the case of a female patient with GT who presented with the chief complaint of gingival bleeding. The patient was given periodontal treatment under platelet transfusion followed by proper oral hygiene instructions. The report discusses periodontal consideration for GT patients.


Medically compromised; periodontal; thrombasthenia

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