Format

Send to

Choose Destination
Acta Otorhinolaryngol Ital. 2009 Jun;29(3):119-26.

Human Papilloma Virus (HPV) in head and neck region: review of literature.

Author information

1
Department of Otolaryngology HN Surgery, University of Pavia, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.

Abstract

The evidence that human papillomavirus infection is related to head and neck squamous cell carcinoma is supported by molecular and epidemiological data. The definition of a distinct subset of head and neck squamous cell carcinoma, independent of the traditional risk factors and with different clinical presentation and outcome, has led to increasing interest in human papillomavirus infection. This review summarizes current knowledge regarding human papillomavirus biology, oncogenic mechanisms, risk factors for transmission, clinical significance and prophylactic strategies.

KEYWORDS:

Head and neck; Human papillomavirus; Oral cavity; Oropharynx; Squamous cell carcinoma

PMID:
20140157
PMCID:
PMC2815356
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center