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Chem Commun (Camb). 2010 Feb 21;46(7):1141-3. doi: 10.1039/b921616b. Epub 2009 Dec 16.

Enzymatically degradable heparin-polyethylene glycol gels with controlled mechanical properties.

Author information

1
Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials Dresden Hohe Str. 6, 01069 Dresden, Germany.

Abstract

A new class of biodegradable materials was prepared by combining polyethylene glycol, heparin, and a matrix metalloproteinase-cleavable peptide sequence into a well-defined hydrogel network which mimics native extracellular matrices in its ability to provide mechanical support and chemical signals as well as elicit a dynamic reciprocal response.

PMID:
20126740
DOI:
10.1039/b921616b
[Indexed for MEDLINE]

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