Objective: To observe the effect of fufang jisheng liujin gao (Compound Mistletoe Fluidextract) on blood pressure in the spontaneous hypertensive rats (SHR) and the renal hypertensive dogs (RHD).
Methods: The blood pressure-decreasing effects of single administration and 14-day consecutive administration of Compound Mistletoe Fluidextract (CMF) in SHR and RHD were investigated and compared with that of niuhuang jiangya wan (Bezoar Hypertension-relieving Pills).
Results: Both single administration and 14-day consecutive administration of CMF had significant hypotensive effects in SHR and RHD.
Conclusion: The hypotensive action of CMF is gradual, but lasts for a longer period, with a dose-effect relationship in a range of doses.