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Chem Soc Rev. 2010 Feb;39(2):495-505. doi: 10.1039/b816354p. Epub 2009 Sep 16.

Cyclodextrin-based bioactive supramolecular assemblies.

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Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, PR China.


Cyclodextrins (CDs) are a class of cyclic oligosaccharides with six to eight D-glucose units linked by alpha-1,4-glucose bonds, and their capability of forming stable complexes with various organic/inorganic/biological molecules and ions makes them attractive as building blocks for the construction of nano-scale supramolecular systems. This tutorial review deals with representative contributions in the construction and the structural characteristics of CD-based supramolecular assemblies as well as their interactions with biologically important substrates. This review is addressed to students and researchers interested in supramolecular chemistry, biochemistry and nanotechnology.

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