Format

Send to

Choose Destination
Mutat Res. 1991 Apr;247(2):231-40.

Chromosome abnormalities in human cancer and leukemia.

Author information

1
Southwest Biomedical Research Institute, Scottsdale, AZ 85251.

Abstract

The meaning and application of chromosomal (cytogenetic, karyotypic) changes in human leukemia and cancer have been succinctly reviewed in this article. Thus, the usefulness of these changes in the diagnosis, classification and prognosis of various leukemic conditions and, more recently, of solid tumors is stressed and their application to molecular studies indicated. The meaning of primary (specific) and additional (secondary) karyotypic changes in malignant and benign tumors is discussed. Tables containing the common cytogenetic changes in leukemias and tumors, including benign ones, are included.

PMID:
2011141
DOI:
10.1016/0027-5107(91)90019-k
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center