Format

Send to

Choose Destination
Dev Psychopathol. 2010 Winter;22(1):1-22. doi: 10.1017/S0954579409990228.

Neurobiological adaptations to violence across development.

Author information

1
University of Washington, Seattle, WA 98195-1525, USA.

Abstract

Developmental adaptations to violent environments involve a multitude of cascading effects spanning many levels of analysis from genes to behavior. In this review, we (a) examine the potentiating effects of violence on genetic vulnerabilities and the functioning of neurotransmitter systems in producing both internalizing and externalizing psychopathology; (b) describe implications of violence exposure for brain development, particularly within the hippocampus and prefrontal cortex; and (c) consider the effects of violence on developing human stress and startle responses. This review integrates literatures on the developmental effects of violence among rodents, nonhuman primates, and humans. Many neurobiological changes that are adaptive for survival in violent contexts become maladaptive in other environments, conferring life-long risk for psychopathology.

PMID:
20102643
PMCID:
PMC2813461
DOI:
10.1017/S0954579409990228
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Cambridge University Press Icon for PubMed Central
Loading ...
Support Center