Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Semin Respir Crit Care Med. 2010 Feb;31(1):66-78. doi: 10.1055/s-0029-1246290. Epub 2010 Jan 25.

Controversies in the treatment of sepsis.

Author information

  • 1Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Clinical Medicine, University of California Davis School of Medicine, Sacramento, CA95817, USA. cesandrock@ucdavis.edu

Abstract

Sepsis is a common illness of intensive care unit patients that carries a high morbidity, mortality, and increases hospital cost. Although mortality from sepsis remains high when compared with other critical illnesses, it has declined over the last few decades due to several adjunctive therapies and focused care programs or guidelines. Many interventions, such as early appropriate antibiotic therapy and lung protective, low tidal volume ventilation are commonplace and carry little controversy in their benefit. However, other therapies still have an unclear benefit and remain controversial. This article discusses the controversial roles of intensive insulin therapy, corticosteroids, and activated protein C in the treatment of sepsis.

Copyright Thieme Medical Publishers.

PMID:
20101549
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Georg Thieme Verlag Stuttgart, New York
    Loading ...
    Write to the Help Desk