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FEBS Lett. 2010 May 17;584(10):2102-11. doi: 10.1016/j.febslet.2010.01.037. Epub 2010 Jan 26.

Chloride channels of intracellular membranes.

Author information

1
UNC Kidney Center and the Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina at Chapel Hill, USA. jedwards@med.unc.edu

Abstract

Proteins implicated as intracellular chloride channels include the intracellular ClC proteins, the bestrophins, the cystic fibrosis transmembrane conductance regulator, the CLICs, and the recently described Golgi pH regulator. This paper examines current hypotheses regarding roles of intracellular chloride channels and reviews the evidence supporting a role in intracellular chloride transport for each of these proteins.

PMID:
20100480
PMCID:
PMC2929963
DOI:
10.1016/j.febslet.2010.01.037
[Indexed for MEDLINE]
Free PMC Article

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