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Eksp Klin Farmakol. 2009 Nov-Dec;72(6):46-8.

[Protective properties of L-carnosine studied in vitro on a hemorrhagic stroke model].

[Article in Russian]


The protective properties of L-carnosine have been studied in vitro on a model of hemorrhagic stroke developed on survival olfactory cortex slices of hypertensive rats after long-term exposure to autoblood. The preliminary application of L-carnosine in a concentration of 5 mg/ml regenerates an activity of glutamatergic and GABAergic components of focal potentials inhibited by autoblood and prevents tissue swelling. L-carnosine protects the bioelectrical activity of nerve cells after their long-term exposure to autoblood and produces an antiedematic effect.

[Indexed for MEDLINE]

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