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Crit Rev Microbiol. 2010;36(1):1-53. doi: 10.3109/10408410903241444.

Epidemiology of invasive mycoses in North America.

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  • 1Department of Pathology, University of Iowa, Iowa City, USA. michael-pfaller@uiowa.edu

Abstract

The incidence of invasive mycoses is increasing, especially among patients who are immunocompromised or hospitalized with serious underlying diseases. Such infections may be broken into two broad categories: opportunistic and endemic. The most important agents of the opportunistic mycoses are Candida spp., Cryptococcus neoformans, Pneumocystis jirovecii, and Aspergillus spp. (although the list of potential pathogens is ever expanding); while the most commonly encountered endemic mycoses are due to Histoplasma capsulatum, Coccidioides immitis/posadasii, and Blastomyces dermatitidis. This review discusses the epidemiologic profiles of these invasive mycoses in North America, as well as risk factors for infection, and the pathogens' antifungal susceptibility.

[PubMed - indexed for MEDLINE]
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