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Am Heart J. 1991 Apr;121(4 Pt 2):1283-8.

Insulin resistance and compensatory hyperinsulinemia: role in hypertension, dyslipidemia, and coronary heart disease.

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1
Department of Medicine, Stanford University School of Medicine, CA.

Abstract

Resistance to insulin-stimulated glucose uptake and hyperinsulinemia may play a central role in the cause and clinical course of patients with non-insulin-dependent diabetes mellitus, high blood pressure, abnormalities of lipoprotein metabolism, and coronary heart disease. This article summarizes the evidence in support of this general hypothesis.

PMID:
2008857
DOI:
10.1016/0002-8703(91)90434-j
[Indexed for MEDLINE]

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