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Vaccine. 2010 Mar 19;28(14):2671-3. doi: 10.1016/j.vaccine.2010.01.007. Epub 2010 Jan 17.

Mumps vaccine associated orchitis: Evidence supporting a potential immune-mediated mechanism.

Author information

1
Infectious Diseases Unit, Department of General Medicine & Murdoch Childrens Research Institute, Royal Children's Hospital Melbourne, Parkville, Victoria 3052, Australia. vanessa.clifford@rch.org.au

Abstract

We report 3 cases of orchitis following vaccination with mumps-measles-rubella (MMR) vaccine, two with an onset within 3 days following vaccination. Orchitis is a common complication of mumps infection, particularly in post-pubertal males, and is also recognized as a very rare complication of mumps vaccination. These cases, discussed together with a comprehensive review of the existing literature regarding post-vaccine orchitis, highlight uncertainty regarding the pathogenesis of post-vaccine orchitis.

PMID:
20085834
DOI:
10.1016/j.vaccine.2010.01.007
[Indexed for MEDLINE]

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