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Cell. 2010 Jan 8;140(1):19-23. doi: 10.1016/j.cell.2009.12.029.

Engineering static and dynamic control of synthetic pathways.

Author information

1
Department of Electrical Engineering and Computer Science, University of California at Berkeley, Berkeley, CA 94720, USA.

Abstract

Maximizing the production of a desired small molecule is one of the primary goals in metabolic engineering. Recent advances in the nascent field of synthetic biology have increased the predictability of small-molecule production in engineered cells growing under constant conditions. The next frontier is to create synthetic pathways that adapt to changing environments.

PMID:
20085699
DOI:
10.1016/j.cell.2009.12.029
[Indexed for MEDLINE]
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