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Clin Infect Dis. 2010 Feb 15;50(4):605-12. doi: 10.1086/650002.

Long-term efficacy and safety of Raltegravir combined with optimized background therapy in treatment-experienced patients with drug-resistant HIV infection: week 96 results of the BENCHMRK 1 and 2 Phase III trials.

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1
State University of New York at Stony Brook, The Rockefeller University, New York, New York, USA.

Abstract

BENCHMRK-1 and -2 are ongoing double-blind phase III studies of raltegravir in patients experiencing failure of antiretroviral therapy with triple-class drug-resistant human immunodeficiency virus infection. At week 96 (combined data), raltegravir (400 mg twice daily) plus optimized background therapy was generally well tolerated, with superior and durable antiretroviral and immunological efficacy, compared with optimized background therapy alone.

PMID:
20085491
DOI:
10.1086/650002
[Indexed for MEDLINE]
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