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BMC Health Serv Res. 2010 Jan 19;10:19. doi: 10.1186/1472-6963-10-19.

Cost-effectiveness of collaborative care for the treatment of major depressive disorder in primary care. A systematic review.

Author information

1
Netherlands Institute for Mental Health and Addiction (Trimbos-Institute), Utrecht, The Netherlands. Ksteenbergen@trimbos.nl

Abstract

BACKGROUND:

The effectiveness of collaborative care for patients with major depressive disorder in primary care has been established. Assessing its cost-effectiveness is important for deciding on implementation. This review therefore evaluates the cost-effectiveness of collaborative care for major depressive disorder in primary care.

METHODS:

A systematic search on economic evaluations of collaborative care was conducted in Pubmed and PsychInfo. Quality of the studies was measured with the Cochrane checklist and the CHEC-list for economic evaluations. Cost-effectiveness and costs per depression-free days were reported.

RESULTS:

8 studies were found, involving 4868 patients. The quality of the cost effectiveness studies, according to the CHEC-list, could be improved. Generally, the studies did not include all relevant costs and did not perform sensitivity analysis. Only 4 out of 8 studies reported cost per QALY, 6 out of 8 reported costs per depression-free days. The highest costs per QALY reported were $49,500, the highest costs per depression-free day were $24.

CONCLUSIONS:

Although studies did not fulfil all criteria of the CHEC-list, collaborative care is a promising intervention and it may be cost-effective. However, to conclude on the cost-effectiveness, depression research should follow economic guidelines to improve the quality of the economic evaluations.

PMID:
20082727
PMCID:
PMC2826303
DOI:
10.1186/1472-6963-10-19
[Indexed for MEDLINE]
Free PMC Article

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