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Int J Cardiol. 2010 Nov 19;145(2):337-339. doi: 10.1016/j.ijcard.2009.12.001. Epub 2010 Jan 15.

Cardiac troponin I is released following high-intensity short-duration exercise in healthy humans.

Author information

1
Brunel University, Uxbridge, Middlesex, UK. Electronic address: rob.shave@brunel.ac.uk.
2
Brunel University, Uxbridge, Middlesex, UK.
3
Liverpool John Moores University, Liverpool, UK.
4
Brunel University, Uxbridge, Middlesex, UK; St. Georges Hospital Medical School NHS Trust, Tooting, London, UK.

Abstract

It has been previously shown that cardiac troponin (cTn) is released in response to prolonged endurance exercise. The influence of short-duration high-intensity exercise upon the release of cTn is not known. We examined cardiac troponin I (cTnI) release pre-, during and post-30 min of high-intensity running exercise in eight recreationally active males (age 29±3 years; VO2peak 53±11 ml kg min(-1)). Following exercise, cTnI increased in six of the eight participants. Four participants showed a minimal response (<0.05 µg/l) post-exercise. In contrast, two participants showed a progressive increase in cTnI (>0.1 µg/l) following exercise which peaked 3-4 h post-exercise. cTnI returned below the detection limit of the assay in all bar one of the participants 24 h post-exercise. These data are the first to show that cTnI can be released following short-duration high-intensity exercise. Clinicians should be aware that exercise-induced release of cTnI is not limited to prolonged endurance activity.

PMID:
20079546
DOI:
10.1016/j.ijcard.2009.12.001
[Indexed for MEDLINE]

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