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Acta Neurol Scand. 2010 Oct;122(4):262-9. doi: 10.1111/j.1600-0404.2009.01304.x. Epub 2010 Jan 11.

Arterial blood pressure vs intracranial pressure in normal pressure hydrocephalus.

Author information

1
Department of Neurosurgery, Division of Clinical Neuroscience, Rikshospitalet University Hospital, Oslo, Norway. per.kristian.eide@rikshospitalet.no

Abstract

OBJECTIVE:

To characterize the association between arterial blood pressure (ABP) and intracranial pressure (ICP) in idiopathic normal pressure hydrocephalus (iNPH) patients, and its impact on outcome of shunt surgery.

MATERIALS AND METHODS:

We analyzed all 35 iNPH patients whose ABP and ICP were recorded simultaneously during 6 years (2002-2007). The static and pulsatile pressures were averaged over consecutive 6-s intervals; the moving correlations between ICP and ABP (static and pulsatile) were determined during consecutive 4-min periods to explore time-related variations.

RESULTS:

Neither static nor pulsatile ABP were altered in iNPH shunt responders. Elevated pulsatile ICP, but normal static ICP, was seen in responders. The time-varying correlations of static and of pulsatile pressures were generally low, and did not differ between shunt responders/non-responders.

CONCLUSIONS:

In iNPH shunt responders, static or pulsatile ABP were not altered and only pulsatile ICP was elevated.

[Indexed for MEDLINE]

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