Format

Send to

Choose Destination
See comment in PubMed Commons below
Lab Chip. 2010 Jan 21;10(2):189-94. doi: 10.1039/b915750f. Epub 2009 Nov 16.

Ultralow power trapping and fluorescence detection of single particles on an optofluidic chip.

Author information

1
School of Engineering, University of CA Santa Cruz, Santa Cruz, CA 95064, USA.

Abstract

The development of on-chip methods to manipulate particles is receiving rapidly increasing attention. All-optical traps offer numerous advantages, but are plagued by large required power levels on the order of hundreds of milliwatts and the inability to act exclusively on individual particles. Here, we demonstrate a fully integrated electro-optical trap for single particles with optical excitation power levels that are five orders of magnitude lower than in conventional optical force traps. The trap is based on spatio-temporal light modulation that is implemented using networks of antiresonant reflecting optical waveguides. We demonstrate the combination of on-chip trapping and fluorescence detection of single microorganisms by studying the photobleaching dynamics of stained DNA in E. coli bacteria. The favorable size scaling facilitates the trapping of single nanoparticles on integrated optofluidic chips.

PMID:
20066246
PMCID:
PMC2863329
DOI:
10.1039/b915750f
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Royal Society of Chemistry Icon for PubMed Central
    Loading ...
    Support Center