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Chem Commun (Camb). 2010 Jan 28;46(4):589-91. doi: 10.1039/b919744c. Epub 2009 Nov 17.

Peptide-based activity-based probes (ABPs) for target-specific profiling of protein tyrosine phosphatases (PTPs).

Author information

1
Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.

Abstract

Synthesis of a novel unnatural amino acid (2-FMPT) for the solid-phase synthesis of peptide-based probes suitable for target-specific activity-based profiling of protein tyrosine phosphatases from crude proteomes is reported.

PMID:
20062871
DOI:
10.1039/b919744c
[Indexed for MEDLINE]

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