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Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2009 Sep-Oct;1(5):540-52. doi: 10.1002/wnan.47.

Nanotechnology in joint replacement.

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  • 1CINN-CSIC, Universidad de Oviedo, Parque Tecnológico de Asturias, Llanera, Asturias, Oviedo, Spain.


This paper reviews the most relevant achievements and new developments in the field of nanomaterials and their possible impact on the fabrication of a new generation of reliable and longer lasting implants for joint replacement. Special emphasis is given to the role of nanocomposites with different microstructural designs: micro-nano composites, nano-nano composites, macro-micro-nano composites as well as bioinspired hierarchical composite materials. These nanostructured materials have opened up an exciting avenue in the design of non-metallic biocompatible, crack growth resistant, tough, and mechanically resistant implants with a lifespan close to the life expectancy of the patients.

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