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Chem Pharm Bull (Tokyo). 2010 Jan;58(1):110-2.

Synthesis and configurational stability of (S)- and (R)-deuteriothalidomides.

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1
Department of Frontier Materials, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Japan.

Abstract

3'-Deuteriothalidomide was synthesized and found to be configurationally five times more stable than thalidomide toward racemization at physiological pH.

PMID:
20045977
[Indexed for MEDLINE]
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