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Kidney Int. 2010 Jan;77(2):85-7. doi: 10.1038/ki.2009.432.

Hydrogen: another gas with therapeutic potential.

Author information

1
[1] Department of Surgery, Division of Cardiothoracic Surgery, University of Alabama at Birmingham, 1900 University Boulevard, Birmingham, AL 35294, USA.

Abstract

Cardinal and colleagues describe the use of molecular hydrogen, the most abundant molecule in the universe, as a treatment for chronic allograft nephropathy (CAN) in a rat model of kidney transplantation. They demonstrate that the addition of hydrogen to the drinking water results in a decrease in the severity of CAN and increased graft survival, and they provide evidence that the mechanism of action could be due to a reduction in reactive oxygen species.

PMID:
20040921
DOI:
10.1038/ki.2009.432
[Indexed for MEDLINE]
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