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Bioinformatics. 2010 Feb 15;26(4):580-1. doi: 10.1093/bioinformatics/btp710. Epub 2009 Dec 29.

GWAF: an R package for genome-wide association analyses with family data.

Author information

1
Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA.

Abstract

GWAF, Genome-Wide Association analyses with Family, is an R package designed for GWAF. It implements association tests between a batch of genotyped or imputed single nucleotide polymorphisms (SNPs) and a binary or continuous trait with user specified genetic model, and generates informative results from the analyses. In addition, GWAF provides functions to visualize results. We evaluated GWAF using a simulated continuous trait and a binary trait dichotomized from the simulated continuous trait with real genotype data from the Framingham Heart Study's SNP Health Association Resource project.

PMID:
20040588
PMCID:
PMC2852219
DOI:
10.1093/bioinformatics/btp710
[Indexed for MEDLINE]
Free PMC Article

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