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Med Sci (Paris). 2009 Dec;25(12):1020-3. doi: 10.1051/medsci/200925121020.

[Antibody databases: IMGT, a French platform of world-wide interest].

[Article in French]

Author information

1
Université Montpellier 2, IMGT, LIGM, Institut de génétique humaine, UPR CNRS 1142, 141, rue de la Cardonille, 34396 Montpellier cedex 5, France. Marie-Paule.Lefranc@igh.cnrs.fr

Abstract

IMGT, the international ImMunoGeneTics information system, was created in 1989 in Montpellier by the Laboratoire d'ImmunoGénétique Moléculaire (LIGM) headed by the Professors Marie-Paule and Gérard Lefranc (University Montpellier 2 and CNRS). IMGT is specialized in the sequences, structures and genetic data of the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibilité complex (MHC), proteins of the IgSF and MhcSF superfamilies, and related proteins of the immune system. The data analysis and the standardization of the annotation are based on IMGT-ONTOLOGY, the first ontology in the domain. IMGT is to-day the international reference system in immunogenetics and immunoinformatics, used in fundamental, medical and biotechnological research and, in particular, in antibody -engineering and humanization.

PMID:
20035673
DOI:
10.1051/medsci/200925121020
[Indexed for MEDLINE]
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