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Bioinformatics. 2010 Feb 15;26(4):576-7. doi: 10.1093/bioinformatics/btp700. Epub 2009 Dec 22.

emPAI Calc--for the estimation of protein abundance from large-scale identification data by liquid chromatography-tandem mass spectrometry.

Author information

1
Human Metabolome Technologies, Inc., Tsuruoka, Yamagata, Japan.

Abstract

emPAI Calc is an open-source web application for the estimation of protein abundance. It uses the correlation between the number of identified peptides and protein abundance in mass spectrometry-based proteomic experiments. The program is the first implementation of our previously reported emPAI algorithm; it calculates the emPAI from the protein identification results obtained by database search engines such as Mascot.

PMID:
20031975
DOI:
10.1093/bioinformatics/btp700
[Indexed for MEDLINE]

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