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Arch Dermatol. 2009 Dec;145(12):1363-6. doi: 10.1001/archdermatol.2009.283.

Lichen planopilaris treated with a peroxisome proliferator-activated receptor gamma agonist.

Author information

1
Departments of Dermatology, The Permanente Medical Group, Vallejo, California, USA. Paradi.Mirmirani@kp.org

Abstract

Primary cicatricial alopecias (PCAs), rare disorders that lead to permanent hair loss, have been poorly understood and are difficult to treat. Lichen planopilaris (LPP)is a prototypical PCA; patients often present with sudden onset of hair loss and clinically significant symptoms of itching, burning, and pain of the scalp. Examination reveals patchy alopecia or a more diffuse thinning of the scalp with characteristic perifollicular erythema and perifollicular scale at the margins of the areas of alopecia.Treatment typically includes use of antiinflammatory medications; although symptoms may improve,hair loss is often progressive.

PMID:
20026843
PMCID:
PMC2937154
DOI:
10.1001/archdermatol.2009.283
[Indexed for MEDLINE]
Free PMC Article
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