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Chem Commun (Camb). 2010 Jan 14;46(2):237-9. doi: 10.1039/b915589a. Epub 2009 Nov 17.

Increasing the hydrophobicity and electrospray response of glycans through derivatization with novel cationic hydrazides.

Author information

  • 1W.M. Keck FTICR Mass Spectrometry Laboratory, Department of Chemistry, North Carolina State University, Raleigh, NC 27695, USA.

Abstract

Novel tags are used to increase the hydrophobicity of glycans and impart a permanent charge yielding as great as a approximately 5-fold increase in electrospray response from both a standard and complex mixture.

PMID:
20024337
DOI:
10.1039/b915589a
[PubMed]
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