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AJNR Am J Neuroradiol. 2010 Sep;31(8):1506-7. doi: 10.3174/ajnr.A1897. Epub 2009 Dec 17.

Marchiafava-Bignami disease with widespread lesions and complete recovery.

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1
Department of Neurology, I-Shou University, Taiwan, Republic of China.

Abstract

MBD is a rare disorder strongly associated with alcoholism. It is characterized pathologically by demyelination and necrosis of the corpus callosum. MBD presents with severe neurologic deficits and significant sequelae developing in most survivors. We report a patient with total clinical recovery. Serial MR imaging demonstrated typical lesions with restricted diffusion in the acute stage and total resolution without atrophy or cystic change.

PMID:
20019108
DOI:
10.3174/ajnr.A1897
[Indexed for MEDLINE]
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