Format

Send to

Choose Destination
See comment in PubMed Commons below
Opt Lett. 2009 Dec 15;34(24):3782-4. doi: 10.1364/OL.34.003782.

Variable optical activation of human cone photoreceptors visualized using a short coherence light source.

Author information

1
Department of Ophthalmology, Medical College of Wisconsin, 925 North 87th Street,Milwaukee, Wisconsin 53226, USA. jrha@mcw.edu

Abstract

It has been shown that after a visible stimulus, optical oscillations of nearly all cone photoreceptors can be observed using long coherence length light and in a few cones using short coherence length light. Here, we show that after exposure to a visible stimulus, a short coherence length imaging source reveals light-evoked oscillation signals in a large number of cones. More than 80% of cones in a given retinal area are activated (modulation in the reflectance signal) after stimulation, and the pattern of their activation can be subjectively classified into one of four categories. The application of light-evoked signal detection techniques for in vivo retinal imaging may prove useful for assessing the functional status of cones in normal and diseased retinae.

PMID:
20016612
PMCID:
PMC3474246
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Optical Society of America Icon for PubMed Central
    Loading ...
    Support Center