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Hematology Am Soc Hematol Educ Program. 2009:587-9. doi: 10.1182/asheducation-2009.1.587.

ASH evidence-based guidelines: what is the role of maintenance therapy in the treatment of multiple myeloma?

Author information

1
Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

Abstract

A 51-year-old male was diagnosed with an IgA multiple myeloma (MM) after having back pain for several months. His bone marrow showed 30% involvement with plasma cells and his cytogenetics showed t(4:14). His beta2-microglobulin was 6.5 mg/dL at diagnosis and he had multiple lytic lesions, along with a creatinine of 2.3 mg/dL and significant anemia. Induction therapy with lenalidomide, bortezomib and dexamethasone was used, and he was able to achieve complete remission after 4 cycles of therapy. He then went on to receive high-dose chemotherapy with a single autologous stem cell transplant. He tolerated it well and now comes to discuss follow-up treatment plans. He wants to discuss maintenance therapy.

PMID:
20008243
DOI:
10.1182/asheducation-2009.1.587
[Indexed for MEDLINE]

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