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Cell. 2009 Dec 11;139(6):1047-9. doi: 10.1016/j.cell.2009.11.037.

The dangers of transcription.

Author information

1
Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany. stephan.mathas@charite.de

Abstract

Transcription is obviously essential, but even a good thing can be dangerous at times. In this issue, Lin et al. (2009) provide evidence that binding of the transcription machinery may predispose genome regions to breakage and translocations that may lead to cancer.

PMID:
20005797
PMCID:
PMC6312720
DOI:
10.1016/j.cell.2009.11.037
[Indexed for MEDLINE]
Free PMC Article

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