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Conf Proc IEEE Eng Med Biol Soc. 2009;2009:1274-7. doi: 10.1109/IEMBS.2009.5334251.

A survival prediction model of hemorrhagic shock in rats using a logistic regression equation.

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  • 1Graduate Program in Biomedical Engineering, Yonsei University, Seoul, Korea. picf@yuhs.ac

Abstract

Hemorrhagic shock is a common cause of death in emergency rooms. Since the symptoms of hemorrhagic shock occur after shock has considerably progressed, it is difficult to diagnose shock early. The purpose of this study was to improve early diagnosis of hemorrhagic shock using a survival prediction model in rats. We measured ECG, blood pressure, respiration and temperature in 45 Sprague-Dawley rats, and then obtained a logistic regression equation predicting survival rates. Area under the ROC curves was 0.99. The Hosmer-Lemeshow goodness-of-fit chi-square was 0.86 (degree of freedom=8, p=0.999). Applying the determined optimal boundary value of 0.25, the accuracy of survival prediction was 94.7%.

PMID:
19964753
DOI:
10.1109/IEMBS.2009.5334251
[PubMed - indexed for MEDLINE]
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